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Showing posts with label The. Show all posts

The Vials Of Crack


Who invented crack?
No one knows for sure. One story credits its discovery to a chemist of the Cali cartel. An early epidemic of crack use occurred in the Bahamas from 1980; Bahamian hospital psychiatry departments recorded a surge of admissions from severely disturbed and psychotic users. In 1983, crack use filtered across the Florida Straits. It took hold in Miami, followed by New York. The first newspaper report of the phenomenon appeared in the Los Angeles Times in 1984, Within a year, crack use had swept across inner city ghettoes throughout America. The first "crack babies" were born.

Crack is actually a less pure variety of free-base cocaine. Unlike old-fashioned free-base, however, its production doesn't involve any flammable solvents. Unlike the hydrochloride salt, free base cocaine vapories at a low temperature. This makes it suitable for smoking.

Crack is usually made by mixing two parts of cocaine hydrochyloride with one part baking soda (sodium bicarbonate: NaHC03) in about 20 ml of water. The solution is then heated gently until white precipitates form. Heating is halted when precipitation stops. The precipitate is filtered and retained. The precipitate may then be washed with water; this procedure is usually omitted in the street product. The product may then be dried for 24 hours under a heat-lamp. Crack is then cut or broken into small 'rocks' weighing a few tenths of a gram.

The traditional method of taking cocaine in the West involves snorting the hydrochloride salt. But absorption through the nasal mucosa is relatively modest. This is because their surface-area is small and cocaine is vasoconstrictive. Classic freebase, on the other hand, is smoked and inhaled directly into the lungs. Therefore much higher doses are possible. Inhalation is followed by an intense euphoric rush. The euphoria doesn't last long. The user becomes irritable and craves more of the drug.

Chronic cocaine-use causes a decrease in the production of enkephalin, one of the brain's natural opioids. This in turn causes a compensatory increase in the number of mu-receptors. The number of unoccupied mu-receptors may be associated with the craving and abstinence syndrome.

After chronic exposure to cocaine, the number of post-synaptic dopamine receptors in the CNS is reduced. The amount of dopamine transporter protein is increased. Tolerance to cocaine's effects does exist over prolonged use; but the extent of this physiological adaptation is relatively modest. The cocaine-user still gets high; but in the absence of cocaine, his pre-synaptic neurons sequester dopamine in the synaptic cleft with greater efficiency. This may induce depression, and sometimes profound despair.

No one ever feels contented after taking cocaine. They just want more. Read More......

The Tools Of The Trade


Cocaine-merchants rely on weighing equipment whose accuracy of calibration is open to variation.
A 1994 survey by the General Accounting Office suggested
that in the previous year around one million US citizens
had used cocaine at least once a week.
Current usage estimates are broadly similar. Read More......

The Health Effects of Cocaine


Cocaine can be snorted, injected and even smoked in some forms of the drug. In all cases cocaine is a strong central nervous system stimulant which affects the brain's processing of dopamine.

Short-Term Effects
When cocaine is used it interferes with the reabsorption of dopamine, a brain chemical associated with pleasure and movement, producing a euphoric effect. Shortly after cocaine is ingested the user may experience the following symptoms:

Constricted blood vessels.

Dilated pupils.

Increased body temperature.

Increased heart rate.

Higher blood pressure.
During the euphoric period after cocaine use, which can last up until 30 minutes, user will experience hyperstimulation, reduced fatigue, and mental alertness. However, some users also experience restlessness, irritability, and anxiety.
During a cocaine binge, when the drug is taken repeatedly, users may experience increasing restlessness, irritability and paranoia. For some users this can lead to a period of paranoid psychosis, with auditory hallucinations and a disconnection with reality.


Long-Term Effects
Repeated cocaine use can cause the following health consequences:

Irregular heart beat.

Heart attack.

Chest pain.

Respiratory failure.

Stroke.

Seizures and headaches.

Abdominal pain and nausea.
Chronic users of cocaine can become malnourished due to the drug's ability to decrease appetite. Each method of taking cocaine can produce specific health effects, including:

Snorting: Chronically runny nose, nosebleeds, loss of smell, hoarseness, and problems swallowing.

Ingesting: Severe bowel gangrene due to a reduction in the flow of blood to the intestines.

Injecting: Severe allergic reactions. Increased risk for contracting HIV, Hepatitis and other blood-borne diseases.
Overdose
Although cocaine overdose is not common, it can occur and can be fatal. Because cocaine affects the heart and respiratory system, an overdose can cause death, especially when the drug is injected or smoked.
An overdose of cocaine can lead to:


Irregular heart beat or heart failure.

High blood pressure resulting in a brain hemorrhage.

Repeated convulsions.

Respiratory failure.
Addiction
Cocaine is highly addictive and those who smoke cocaine appear to develop an addiction to the drug more rapidly that those who snort it. However, even those who snort cocaine can find themselves addicted.
Cocaine users report that they are never able to achieve the "high" they felt the first time that they used the drug. A tolerance to the drug is developed so that the euphoric feeling users get is not as intense nor does it last as long.

When cocaine is injected, the euphoric feeling can last from 15 to 30 minutes, but when it is smoked, in may last only five to 10 minutes, causing the user to use more cocaine more often to try to maintain that high.


Withdrawal
When cocaine users stop using cocaine, or when they end a cocaine binge, they immediately experience a "crash" which includes depression, fatigue, lack of pleasure, anxiety, irritability, sleepiness and a strong craving for more cocaine.
Some people experience agitation and extreme suspicion when they quit using cocaine, but cocaine withdrawal usually does not have visible physical symptoms like vomiting, chills and tremors that occur with the withdrawal of other drugs. Read More......

History of Cocaine, Recreational Use


Before the 1860's cocaine was only available in leaf form. The cocaine content of coca leaf is under 1%. After cocaine was isolated from coca leaf, it was available legally in concentrations that were nearly 100% pure.

The active ingredient from the coca leaf was first isolated by Albert Niemann. In 1860 he gave the compound the name cocaine.

Cocaine was first used recreationally in the 1860s. People were using cocaine as a recreational drug almost as soon as it was synthesized. A few years after its synthesis, cocaine appeared in cigarettes, ointments, nasal sprays, and preparations sold as tonics.

These legal tonics had coke mixed with other substances, including morphine, codeine, and opium. They were sold in a liquid form, and cured "whatever ailed you". The powder itself was used recreationally almost as soon as it was isolated.

The most popular of cocaine laced products was Mariani Wine (Vin Mariani). It was a wine and cocaine mixture that was launched in 1863. Nearly all popular personalities of the day used and endorsed it. These Vin Maria lovers included: Queen Victoria, The Pope, Thomas Edison, and others.

Sir Arthur Conan Doyle's "Sign Of Four" was written about 30 years after the synthesis of cocaine. In the book Sherlock Holmes (an intravenous cocaine and morphine user) gives reasons for his cocaine and morphine use "...I abhor the dull routine of existence. I crave for mental exaltation..."

The negative effects of cocaine addiction were soon noticed and between 1887 and 1914 forty six states had passed laws aimed at controlling it.

The press began to associate cocaine powder use with societies outcast in the 1890s. Criminals, prostitutes, pimps, gamblers, and racial minorities were usually the target.

Then in 1914 the U.S. federal government classified cocaine as a narcotic (which it is not) and outlawed it. After passing the Harrison Narcotics Act of 1914, the only way a person could get cocaine was with a prescription, or illegally.

In the 1920s cocaine use declined, and that decline was to become more so in the 1930s, when amphetamine (speed) became popular among drug users.



Amphetamine
Amphetamine was appealing to the cocaine user because the high it produced was much like cocaine's. It did not deliver quite the same peak, but its effects lasted longer.

More significantly, it was cheap, readily available and legal. With the appearance of legally obtainable amphetamine (readily available by the late 1930s), cocaine use declined considerably. Its use remained low until all amphetamines, including meth became illegal in the 1960s.

This made amphetamine more difficult to obtain, so dealers and users switched back to the neglected cocaine, and the first flurries of the current blizzard arrived. Cocaine is not a drug that burst onto the scene sometime in the 1960s. It was used as a recreational drug, a century before. Read More......

The History Of Cocaine


Old History of Cocaine

In traditional Indian cultures, Mama Coca was considered a benevolent deity. She was regarded as a sacred goddess who could bless humans with her power.

Before the coca harvest, the harvester would sleep with a woman to ensure Mama Coca would be in a favorable mood. Typically, a decoction of coca and saliva was rubbed onto the male organ to prolong erotic ecstasy.

Traditionally, the leaves have been chewed for social, mystical, medicinal and religious purposes. Coca has even been used to provide a measure of time and distance. Native travelers sometimes described a journey in terms of the number of mouthfuls of coca typically chewed in making the trip.

South American Indians have used cocaine as it occurs in the leaves of Erythroxylum coca (also called Erythroxylon coca) for at least 5000 years. In its native habitat, the coca plant is resistant to drought and disease. It needs no irrigation. Coca can be harvested several times a year. Traditionally, chewing the sacred leaf promotes contact with the spirit world.

Chewing or smoking coca leaves invigorates the user, allowing him to absorb the plant's magical powers and protect body and spirit alike.

The introduction of coca to England was pioneered early in nineteenth century by the Royal Botanical Gardens at Kew; but the plant has yet to find a place in orthodox Western horticulture.

In pre-Columbian times, the coca leaf was reserved for Inca royalty. The natives subsequently used it for mystical, religious, social, nutritional and medicinal purposes.

They exploited its stimulant properties to ward off fatigue and hunger, enhance endurance, and to promote a benign sense of well-being.

It was initially banned by the Spanish. But the invaders discovered that without the Inca "gift of the gods", the natives could barely work the fields, or mine gold. So it came to be cultivated by the Catholic Church.

Coca leaves were distributed three or four times a day to the workers during brief rest-breaks. Returning Spanish conquistadors introduced it to Europe. Coca was touted as "an elixir of life".

In 1814, an editorial in Gentleman's Magazine urged researchers to begin experimentation so that coca could be used as "a substitute for food, so that people could live a month, now and then, without eating..."



New History of Cocaine
The active ingredient (an alkaloid) from the coca plant (erythroxylum) was first isolated by a chemist named Albert Niemann. In 1860 he gave the compound the name cocaine.

The drug induces a sense of exhilaration in the user primarily by blocking the reuptake of the neurotransmitter dopamine in the midbrain.

Soon after it was first synthesized, cocaine was available almost everywhere. Sometimes available in powder form, it was also mixed with various other products like wine and cigarettes. Doctors dispensed cocaine as an antidote to morphine addiction. Unfortunately, some patients made a habit of combining them.

Freud described cocaine as a magical drug. He wrote a song of praise in its honor and practiced extensive self-experimentation. To Sherlock Holmes, cocaine was "so transcendentally stimulating and clarifying to the mind that its secondary action is a matter of small moment".

Cocaine is now an integral part of the world economy. Its street price reflects the competitive pressures of today's global marketplace.

Coca has been grown commercially in Sri Lanka, Taiwan, Indonesia, Nigeria, Malaysia and Japan. The first cocaine cartel was formed, not in Columbia, but in Amsterdam.

Founded in 1910, the Cocaine Manufacturers Syndicate included pharmaceutical giants Merck, Sandoz and Hoffman-LaRoche. At present, however, most production occurs in clandestine laboratories in South America.

Since the 1980's, cocaine has become a significant export-earner for many poor South American countries. In the year 2000, South America exported some 1000 tons of refined cocaine.

In the 1980s, millions of drug-naive Americans were introduced to 'decocainised' coca tea imported from South America. In Peru, the legitimate cultivation of coca, and the production of all cocaine licensed for pharmaceutical export, was controlled by the government's own National Enterprise Of Coca.

In a bid to expand and diversify its product range, the National Enterprise Of Coca promoted the benefits of coca in the form of a wholesome traditional beverage.

This state-sponsored export-drive was successful: overseas demand proved brisk. From 1983, 'Inca Health Tea' sold especially well in the North American market.

Lemongrass and other flavors were added to cater to American palates. Soon mate de coca could be bought in tea-shops and grocery stores in US cities.

Mate de coca is an agreeable and invigorating mood-brightener. It is also benign, patients at the San Francisco National Addiction Research Foundation, for instance, were encouraged in the 1980s to drink as much mate de coca as they desired to help wean themselves off cocaine.

When consumed in generous quantities, the tea is good at easing drug-cravings; but this is because the average tea-bag contains 5 milligrams of cocaine.

Inca tea is now illegal in the USA.



The CIA And Cocaine
The cocaine trade continues to spawn eyebrow-raising alliances. Declassified documents now available at the CIA web site disclose that in the 1980s CIA operatives teamed up with cocaine dealers in the fight against Communism.

In 1979, the people of the small Central American country of Nicaragua overthrew the US-backed Samoza dictatorship. To the horror of US policy-makers, the Nicaraguans then elected a left-wing government.

Investigative journalist Richard Webb, in his book Dark Alliance first revealed how profits from cocaine sold in Los Angeles and Miami were used by the CIA to fund, and buy guns for the anti communist contra rebels.

Suitcases stuffed with coke-tainted US dollars were dispatched to Nicaragua to foment insurrection and civil war.

According to Internic records in 1998 the domain cocaine.com was registered in the name of the CIA. Read More......