DRUGS, Marijuana, Cocaine, Xanax , Adderall, Ecstasy, Heroin, LSD, PCP, Magic Mushrooms, Alcohol

Drugs have a strong hold on one who is addicted. Often nothing else matters. However, it's important to remember that the only thing stronger than drug addiction is your willpower. If you make the decision to quit doing drugs you can, as long as you realize the process that needs to take place. Quitting drugs is a team effort weather it be a team of people you know or are just meeting for the first time. Making the decision to quit is the hardest part. Instructions 1 Make the decision to quit doing drugs. The hardest yet most essential step is to make the decision on your own. Drug users never truly quit until they make a firm decision. Once you have realized that you will be better off without drugs in your life, support your decision by letting everyone know of the change your will be making. Tell family, friends and most important the people you associate with while doing drugs. Be ready for the support some will offer as well as the bad attitude some will surely give. Stay strong in your decision after talking with everyone. 2 Get professional help. The chances of someone successfully quitting drugs without rehab or some sort of help is nearly nil. You may want to consider checking yourself into a drub rehabilitation clinic. To find more information about a clinic near you, call the Drug Rehab Hotline. In addition, you can attend a local 12-step program where you will attend meetings once a week with others going through the same life change as you. Often drug counselors can be helpful. They offer you one-on-one time with somebody who can help create changes in your life that will help you to achieve your goal. 3 Change your social environment. Almost every drug user associates with a group of friends that also do drugs. These may be the only friends that you have. As hard as it may be, you need to realize how hazardous it is to your decision to quit to continual to hang around people that do drugs. Never expect yourself as a drug user to be strong enough to be in the presence of drugs. If they are real friends they will understand and support your decision, if they aren't then unfortunately new friends may be in order. 4 Create a follow-up system. It is important to stay on path even after you completed rehab or counseling. Once you are drug user, the ability to use again is always in your system. Your will to stop doing drugs has to have a stronger hold on you than drugs do. Many times rehabilitation centers offer sober living environments after you successfully go through rehab. Sober living homes are basically a normal living environment with roommates except with a few more restrictions. You can live your life normally but you and the people living with your create a check system for each other. If sober living doesn't interest you, you can create a check system with somebody you trust. Let them help you create rules and boundaries. Allow them to question you and demand that you abide by the rules you both set. 5 Monitor your time. Keeping busy with little down time to falter will greatly increase your chances of staying sober. Work a steady job and maybe even join a few activities you enjoy. Do things that make you happy that don't disturb your sober living. Keep the change in your life real and make no excuses for yourself. Read more: http://bardrugs.blogspot.com/2011/05/heroin.html Read More......

HOW TO QUIT COCAINE
The high from crack cocaine is intensely rewarding. But the experience is short-lived. Such immense well-being is unsustainable because its mechanisms don't subvert the systems of homeostatic feedback inhibition of the brain. So it's reckless to try crack cocaine at all - at least until one's death-bed - because its euphoric effect is so extraordinarily hard to forget. If one succumbs to curiosity, and finds out what one is missing, then the rest of one's life may pall in comparison. For there is nothing in life that's naturally so enjoyable as crack. Tragically, the user's family and loved ones may suffer the price of pleasure almost as severely as the addict.
So is a crackhead inescapably doomed to an early grave? Or are there ways (s)he can escape from the abyss?

Perhaps. Most of the GIs who got hooked on unmistakably physically addictive heroin in Vietnam kicked the habit when they returned to the USA. The veterans quit, often without undue difficulty, because most of the "conditioned cues and reinforcers" associated with narcotic drug-use in South-East Asia were missing back home.

Thus a complete change of environment, especially a holiday in the company of supportive family and (drug-free) friends, can help break a user's self-destructive cycle of coke-binges. The brain is given time to recover. Cue-elicited craving is a major cause of relapse in recovering coke-users. Indeed this cue-elicited craving may even increase during the first few months of withdrawal.

Good food, particularly an idealised stone-age diet [fruit, vegetables, nuts, seeds, wholemeal bread, pasta, rice etc] should help. Regular vigorous exercise is useful as well [and probably Faith In Jesus, though this isn't always a realistic goal]. Another option is joining Cocaine Anonymous.

More controversially, "cocaine vaccines" may soon be licensed. They are designed to induce drug-specific antibodies in the bloodstream. In theory, cocaine-specific antibodies which sequester the drug before its passage into the brain will prevent the relapsing user getting high. Perhaps children "at risk" will be vaccinated at an early age. The possible coercive use of "vaccines against pleasure" raises profound ethical problems.


Cocaine addicts motivated to quit might consider a course of the antiepileptic drug vigabatrin (Sabril), though it isn't licensed in the USA. Vigabatrin is an irreversible inhibitor of gamma-aminobutyric acid transaminase (GABA-T). GABA-T the enzyme responsible for the catabolism of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Feedback inhibition between the "feel good" dopaminergic and GABA-ergic neurotransmitter systems explains vigabatrin's therapeutic "antidopaminergic" action. Vigabatrin is a relatively safe drug. Even so, its use sometimes causes colour vision defects; the most common adverse side-effects reported are sleepiness and fatigue.

A future option for cocaine addicts who want to quit may be taking a dual dopamine/serotonin releaser. PAL-287 is a rationally-designed drug aimed at treating stimulant dependence while having minimal "abuse potential" of its own. Much more research will be needed before it ever gets a product license.

Another future option may be the benztropine analog JHW007. It serves as a functional antagonist to cocaine. JHW007 has a high affinity for the dopamine transporter with minimal cocaine-like subjective and behavioural effects.

Some drug-pundits recommend Total Abstinence from chemical assistance: "Just Say No." The ex-addict is encouraged to renounce "unnatural" chemical highs altogether. This course of action may indeed be prudent given our bug-ridden genome and current crop of misbegotten street drugs. Unfortunately, opting to embrace godliness, hard work and clean living isn't always the recipe for a happy life either.

For many cocaine-users have a pre-existing psychiatric disorder - even by the touchstone of today's impoverished conception of mental health. In effect, such users are self-medicating, even if they ostensibly take cocaine hedonistically "for kicks". Such users need more effective medicine to flourish. So in place of cocaine, the option of taking one or more clinically therapeutic mood-brighteners [e.g. desipramine (Norpramin), a noradrenaline reuptake inhibitor; venlafaxine (Effexor), milnacipran (Ixel) or duloxetine (Cymbalta), dual-action serotonin and noradrenaline reuptake inhibitors; perhaps a glutamate-enhancing agent such as modafinil (Provigil); or more daringly, amineptine (Survector), a dopamine reuptake inhibitor; and/or anti-anxiety agents e.g. benzodiazepines] may be considered instead.

Alternatively, if the user wishes to Say No To Drugs completely, then a "natural", gentle mood-brightener and anti-anxiety agent, hypericum (St John's wort), may be taken indefinitely. Unfortunately, this traditional herbal medicine is not a dependable remedy for deep melancholic depression - coke-induced or otherwise.

S-Adenosyl-L-methionine (SAMe) is another natural antidepressant. But its efficacy in treating cocaine-induced depression is untested in controlled clinical trials.


Inevitably, present-day mood-brighteners, whether herbal or clinical, won't stand comparison with tomorrow's revolutionary designer-drugs. Nor do they deliver the rapturous but addictive rush of a fast-acting euphoriant. Contemporary therapeutic mood-boosters yield desperately little joy compared to the lifetime of genetically pre-programmed superhealth on offer to our descendants. But our legacy DNA didn't design us to be happy. So for now, the dirty chemical stopgaps licensed for use in contemporary clinical medicine are often better than nothing at all. Read More......

Cocaine is a powerful constrictor of blood vessels and a local anaesthetic. It is also a potent psychostimulant. The physical effects of cocaine on the user include excitement, alertness, tachycardia, pupillary dilatation, raised body-temperature, hypertension, brochodilation, enhanced glucose availability, and increased motor activity - all part of the "fight or flight" syndrome.

Taking cocaine also also gets you high. Its half-life in the plasma, however, is only 50 minutes; and the euphoria soon fades. Freebase/crack users desire more of the drug far sooner than users of the hydrochloride salt.

The rewarding properties of cocaine derive mainly from its effects on the neurotransmitter dopamine. The dopamine system is involved in the control of mood, motivation, cognition, locomotion, sexuality and endocrine function. There are only some 30-40 thousand dopamine neurons in the brain, but both the axons and dentrites of the dopamine neurons are unusually well arborised - with as many as 100,000 synapses for each dopaminergic neuron. Their distinctive morphology reflects dopamine's role in the "encephalisation of emotion".

Cocaine induces elation primarily by blocking the dopamine transporter. The blockade increases the availability of free dopamine in the mesolimbic pleasure-centres of the brain. Degree of transporter occupancy is correlated with the intensity of euphoria. Higher doses and faster routes of administration create vivid memories and intense cravings. But the biological substrates of pure pleasure remain elusive. Investigation of the possible final common pathway of pleasure in the brain continues. Endorphins and enkephalins activating receptors in the ventral pallidum apparently play a role too, as does the orbitofrontal cortex.

Recent research highlights the role of the sigma1 receptors in cocaine-induced euphoria. Co-administering a sigma1 agonist makes taking cocaine even more enjoyable. Sigma1 agonists like igmesine are also under investigation as potential antidepressants. Conversely, taking a sigma1 receptor antagonist makes cocaine use unrewarding.


Whatever its mechanisms, and unlike most clinically-approved mood-brighteners, cocaine is a pro-sexual drug. Taken before sex, it can induce prolonged and intense orgasm. Cocaine-induced lovemaking, however, is not especially warm or empathetic. Read More......

Who invented crack?
No one knows for sure. One story credits its discovery to a chemist of the Cali cartel. An early epidemic of crack use occurred in the Bahamas from 1980; Bahamian hospital psychiatry departments recorded a surge of admissions from severely disturbed and psychotic users. In 1983, crack use filtered across the Florida Straits. It took hold in Miami, followed by New York. The first newspaper report of the phenomenon appeared in the Los Angeles Times in 1984, Within a year, crack use had swept across inner city ghettoes throughout America. The first "crack babies" were born.

Crack is actually a less pure variety of free-base cocaine. Unlike old-fashioned free-base, however, its production doesn't involve any flammable solvents. Unlike the hydrochloride salt, free base cocaine vapories at a low temperature. This makes it suitable for smoking.

Crack is usually made by mixing two parts of cocaine hydrochyloride with one part baking soda (sodium bicarbonate: NaHC03) in about 20 ml of water. The solution is then heated gently until white precipitates form. Heating is halted when precipitation stops. The precipitate is filtered and retained. The precipitate may then be washed with water; this procedure is usually omitted in the street product. The product may then be dried for 24 hours under a heat-lamp. Crack is then cut or broken into small 'rocks' weighing a few tenths of a gram.

The traditional method of taking cocaine in the West involves snorting the hydrochloride salt. But absorption through the nasal mucosa is relatively modest. This is because their surface-area is small and cocaine is vasoconstrictive. Classic freebase, on the other hand, is smoked and inhaled directly into the lungs. Therefore much higher doses are possible. Inhalation is followed by an intense euphoric rush. The euphoria doesn't last long. The user becomes irritable and craves more of the drug.

Chronic cocaine-use causes a decrease in the production of enkephalin, one of the brain's natural opioids. This in turn causes a compensatory increase in the number of mu-receptors. The number of unoccupied mu-receptors may be associated with the craving and abstinence syndrome.

After chronic exposure to cocaine, the number of post-synaptic dopamine receptors in the CNS is reduced. The amount of dopamine transporter protein is increased. Tolerance to cocaine's effects does exist over prolonged use; but the extent of this physiological adaptation is relatively modest. The cocaine-user still gets high; but in the absence of cocaine, his pre-synaptic neurons sequester dopamine in the synaptic cleft with greater efficiency. This may induce depression, and sometimes profound despair.

No one ever feels contented after taking cocaine. They just want more. Read More......

From Chewing Coca Leaves To Crack
Chewing Coca Leaves. Coca consumption was originally the prerogative of the Inca elite. Today, most of the natives indulge as well. Coca is also consumed as the highly esteemed coca de mate.

Drinking coca tea tends to soothe the stomach, so it's good for digestive problems. Coca de mate is less likely to induce jitteriness than coffee. It is a rather more effective mood brightener too.



Cocaine Sulfate - pasta, basuco, basa, pitillo, paste. This is the low grade stuff that reaches the urban slums of South America. The sulfate is the intermediate stage between the coca leaf and the finished cocaine hydrochloride crystal.

Coca leaves are stripped from the plant. They are put in plastic pit with a solution of water and sulfuric acid. A bare footed man will climb in the pit, step on the mess and move it around with his hands.



Cocaine Hydrochloride - an odorless, white crystalline powder. It has a bitter, numbing taste. This is the type of cocaine available in most cities.

Making cocaine hydrochloride is quite complicated. The pasta is first washed in kerosene. It is then chilled. The kerosene is removed. Gas crystals of crude cocaine are left at the bottom of the tank.

Typically, the crystals are dissolved in methyl alcohol. They are then re-crystallized and dissolved once more in sulfuric acid. Further washing, oxidation and separation procedures involve potassium permanganate, benzole, and sodium carbonate.



Freebase And Crack Cocaine. Freebase and crack cocaine are derived from cocaine hydrochloride which has been chemically treated to free the potent base material from the salt.

Freebase was originally produced by a dangerous four or five step process in which the hydrochloride salt was heated with water and a volatile liquid such as ether.

Base cocaine in the form of crack is safer to produce but it is no less addictive. Crack and freebase are indissoluble in water, so they can't be injected or sniffed easily.

Instead, base is usually smoked from pipes, burnt on a piece of tin foil, or mixed with tobacco and marijuana in a smokable joint.

The euphoric rush comes within a few seconds (even faster than from injecting cocaine hydrochloride). Initially, the user may experience a profound sense of power, mastery, cleverness and uninhibited desire. But the exhilaration usually starts to fade within a few minutes.



Cocaine Use
Physical constraints ensure that even the most ardent coquero can get only a modest amount of cocaine into his bloodstream. Coca induced heart-attacks and strokes are thus extremely rare among traditional users.

In recent decades, however, there have been changes in cocaine's route of administration, patterns of use, the technology of cocaine production, and typical dosages.

Crack is actually a less pure sort of freebase cocaine. Unlike old fashioned freebase, however, its production doesn't involve any flammable solvents.

Crack is usually made by mixing two parts of cocaine hydrochloride with one part baking soda in some water. The solution is then heated gently until white precipitates form. Crack is then cut or broken into small rocks weighing a few tenths of a gram.

The traditional method of taking cocaine in the west involved snorting the hydrochloride salt. But absorption through the nasalmucousa is relatively modest.

This is because their surface-area is small and cocaine is vasoconstrictive. Freebase, on the other hand, is smoked and inhaled directly into the lungs. Therefore much higher doses are possible. Inhalation is followed by an intense euphoric rush.

Chronic cocaine use causes a decrease in the production of enkephalin, one of the brain's natural opioids. This in turn causes a compensatory increase in the number of mu-receptors. The number of unoccupied mu-receptors may be associated with the craving and abstinence syndrome.

After chronic exposure to cocaine, the number of post-synaptic dopamine receptors in the CNS is reduced. The amount of dopamine transporter protein is increased.

Tolerance to cocaine's effects does exist over prolonged use; but the extent of this physiological adaptation is relatively modest. The cocaine user still gets high; but in the absence of cocaine, his pre-synaptic neurons sequester dopamine in the synaptic cleft with greater efficiency.

This may induce depression, sometimes severe. Read More......

Crack is a form of freebase cocaine that is best suited to smoking. Smoking street cocaine (cocaine hydrochloride) is possible but a lot of the cocaine gets destroyed when heated.

Cocaine hydrochloride requires a high temperature to ignite, freebase cocaine requires a much lower temperature to ignite.

Converting cocaine to freebase is fairly easy and the resulting product is ideal for smoking. Very little of the cocaine is destroyed in the heating process when smoking freebase cocaine.

The reason people smoke freebase cocaine is because it provides a feeling that is similar to the effect one gets from injecting cocaine. But smoking freebase cocaine does not require needles.

See how to make crack and freebase cocaine for further information on freebase cocaine. Read More......